教員紹介 詳細

主な業績

原著論文・総説
1. Niwano Y, Kohzaki H, Shirato M, Shishido S, Nakamura K: Anti-osteoporotic mechanisms of polyphenols elucidated based on in vivo studies using ovariectomized animals. Antioxidants (Basel), 11:217, 2022
2. Tenkumo T, Aobulikasimu A, Asou Y, Shirato M, Shishido S, Kanno T, Niwano Y, Sasaki K, Nakamura K: Proanthocyanidin-rich grape seed extract improves bone loss, bone healing, and implant osseointegration in ovariectomized animals. Sci Rep, 10:8812, 2020
3. Nakamura K, Shirato M, Shishido S, Niwano Y, Kanno T, Sasaki K, Lingström P, Örtengren U: Reactions of dental pulp to hydrogen peroxide photolysis-based antimicrobial chemotherapy under ultraviolet-A irradiation in rats. J Photochem Photobiol B, Biology, 212:112042, 2020
4. Matsuo H, Hirose T, Mokudai T, Nonaka K, Niwano Y, Sunazuka T, Takahashi Y, Ōmura S, Nakashima T: Absolute structure and anti-oxidative activity of chaetochiversin C isolated from fungal strain Neocosmospora sp. FKI-7792 by physicochemical screening. J Gen Appl Microbiol, 26:181-187, 2020. 2020
5. Miyano R, Matsuo H, Mokudai T, Noguchi Y, Higo M, Nonaka K, Niwano Y, Sunazuka T, Shiomi K, Takahashi Y, Ōmura S, Nakashima T: Trichothioneic acid, a new antioxidant compound produced by the fungal strain Trichoderma virens FKI-7573. J Biosci Bioeng, 129:508-513, 2020
6. Matsuo H, Mokudai T, Higo M, Nonaka K, Nagano Y, Nagahama T, Niwano Y, Takahashi Y, Ōmura S, Nakashima T: Cipralphelin, a new anti-oxidative N-cinnamoyl tripeptide produced by the deep sea-derived fungal strain Penicillium brevicompactum FKJ-0123. J Antibiot, 72:775-778, 2019
7. Shirato M, Nakamura K, Tenkumo T, Kano Y, Ishiyama K, Kanno T, Sasaki K, Niwano Y, Matsuura H: Oral mucosal irritation potential of antimicrobial chemotherapy involving hydrogen peroxide photolysis with high-power laser irradiation for the treatment of periodontitis. J Photochem Photobiol B, Biology, 201:111633, 2019
8. Niwano Y, Iwasawa A, Tsubota K, Ayaki M, Negishi K: Protective effects of blue light-blocking shades on phototoxicity in human ocular surface cells. BMJ Open Ophthalmol, 4: e000217, 2019
9. Nakamura K, Shirato M, Tenkumo T, Kanno T, Westerlund A, Örtengren U, Sasaki K, Niwano Y: Hydroxyl radicals generated by hydrogen peroxide photolysis recondition biofilm-contaminated titanium surfaces for subsequent osteoblastic cell proliferation. Sci Rep, 9:4688, 2019
10. Ueda T, Ueda K, Ito K, Ogasawara K, Kanetaka H, Mokudai T, Niwano Y, Narushima T: Visible-light-responsive antibacterial activity of Au-incorporated TiO2 layers formed on Ti-(0-10)at%Au alloys by air oxidation. J Biomed Mater Res Part A, 107:991-1000, 2019
11. Nakamura K, Ankyu S, Nilsson F, Kanno T, Niwano Y, Vult von Steyern P, Örtengren U: Critical considerations on load-to-failure test for monolithic zirconia molar crowns. J Mech Behav Biomed Mater, 87:180-189, 2018
12. Nakazawa K, Nakamura K, Harada A, Shirato M, Inagaki R, Örtengren U, Kanno T, Niwano Y, Egusa H: Surface properties of dental zirconia ceramics affected by ultrasonic scaling and low-temperature degradation. PloS one 13:e0203849, 2018
13. Miyano R, Matsuo H, Nonaka K, Mokudai T, Niwano Y, Shiomi K, Takahashi Y, Ōmura S, Nakashima T: Pochoniolides A and B, new antioxidants from the fungal strain Pochonia chlamydosporia var. spinulospora FKI-7537. J Biosci Bioeng, 126:661-666, 2018
14. Shishido S, Miyano R, Nakashima T, Matsuo H, Iwatsuki M, Nakamura K, Kanno T, Egusa H, Niwano Y: A novel pathway for the photooxidation of catechin in relation to its prooxidative activity. Sci Rep, 8:12888, 2018
15. Nakamura K, Tenkumo T, Mokudai T, Shirato M, Ishiyama K, Kanno T, Sasaki K, Niwano Y: Potential adverse effects of antimicrobial chemotherapy based on ultraviolet-A irradiation of polyphenols against the oral mucosa in hamsters and wounded skin in rats. J Photochem Photobiol B, Biology, 187:96-105, 2018
16. Ankyu S, Nakamura K, Harada A, Inagaki R, Kastuda Y, Kanno T, Niwano Y, Örtengren U, Egusa H: Influence of microscale expansion and contraction caused by thermal and mechanical fatigue on retentive strength of CAD/CAM-generated resin-based composite crowns. J Mech Behav Biomed Mater, 86:89-97, 2018
17. Jin G, Asou Y, Ishiyama K, Okawa A, Kanno T, Niwano Y: Proanthocyanidin-rich grape seed extract modulates intestinal microbiota in ovariectomized mice. J Food Sci, 83(4):1149-1152, 2018
18. Kimura T, Tajima A, Inahashi Y, Iwatsuki M, Kasai H, Mokudai T, Niwano Y, Shiomi K, Takahashi Y, Ōmura S, Nakashima T: Mumiamicin: Structure and bioactivity of a new furan fatty acid from Mumia sp. YSP-2-79. J Gen Appl Microbiol, 64(2):62-67, 2018
19. Sheng H, Ogawa T，Niwano Y，Sasaki K，Tachibana K: Effects of polyphenols on doxorubicin-induced oral keratinocyte cytotoxicity and anticancer potency against oral cancer cells. J Oral Pathol Med, 47(4):368-374, 2018
20. Jin G, Aobulikasimu A, Piao J, Aibibula Z, Koga D, Ochi H, Ishiyama K, Kanno T, Niwano Y, Okawa A, Asou Y: Proanthocyanidin-rich grape seed extract prevent estrogen deficiency-induced metabolic disorders. J Med Dent Sci, 62(2):45-50, 2018
21. 冨並加奈子、金髙弘恭、目代貴之、庭野吉己：低温大気圧プラズマ照射により生成される活性酸素種の定量評価．　東北大学歯学雑誌 35・36:87-95, 2017
22. Niwano Y, Konno K, Matayoshi T, Nakamura, K., Kanno, T., Sasaki, K.: Oral mucosal irritation study in hamster to evaluate a therapeutic apparatus using hydrogen peroxide photolysis for periodontitis treatment. Regul Toxicol Pharmacol, 90:206-213, 2017
23. Kanno T, Nakamura K, Ishiyama K, Yamada Y, Shirato M, Niwano Y, Kayaba C, Ikeda K, Takagi A, Yamaguchi T., Sasaki K: Adjunctive antimicrobial chemotherapy based on hydrogen peroxide photolysis in non-surgical treatment for moderate to severe periodontitis: a randomized clinical trial. Sci Rep, 7(1):12247, 2017
24. Shirato M, Nakamura K, Kanno T, Lingström P, Niwano Y, Örtengren U: Time-kill kinetic analysis of antimicrobial chemotherapy based on hydrogen peroxide photolysis against Streptococcus mutans biofilm. J Photochem Photobiol B, Biology, 173:434-440, 2017
25. Nakamura K, Shirato M, Kanno T, Lingström P, Örtengren U, Niwano Y: Photo-irradiated caffeic acid exhibits antimicrobial activity against Streptococcus mutans biofilms via hydroxyl radical formation. Sci Rep, 7(1):6353, 2017
26. Tominami K, Kanetaka H, Sasaki S, Mokudai T, Kaneko T, Niwano Y: Cold atmospheric plasma enhances osteoblast differentiation. PLoS One, 12(7):e0180507, 2017
27. Niwano Y, Tada M, Tsukada M: Antimicrobial intervention by photoirradiation of grape pomace extracts via hydroxyl radical generation. Front Physiol, 8:728, 2017
28. Sato E, Mori T, Mishima E, Suzuki A, Sugawara S, Kurasawa N, Saigusa D, Miura D, Morikawa-Ichinose T, Saito R, Oba-Yabana I, Oe Y, Kisu K, Naganuma E, Koizumi K, Mokudai T, Niwano Y, Kudo T, Suzuki C, Takahashi N, Sato H, Abe T, Niwa T, Ito S: Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease. Sci Rep, 6:36618, 2016
29. Sato H, Niwano Y, Nakamura K, Mokudai T, Ikai H, Kanno T, Egusa H: Efficacy and safety of a therapeutic apparatus using hydrogen peroxide photolysis to treat dental and periodontal infectious diseases. J Toxicol Sci, 41(6):793-799, 2016
30. Ishiyama K, Nakamura K, Kanno T, Niwano Y: Bactericidal action of photodynamic antimicrobial chemotherapy (PACT) with photosensitizers used as plaque-disclosing agents against experimental biofilm. Biocontrol Sci, 21(3):187-191, 2016
31. Nakamura K, Shirato M, Kanno T, Örtengren U, Lingström P, Niwano Y: Antimicrobial activity of hydroxyl radicals generated by hydrogen peroxide photolysis against Streptococcus mutans biofilm. Int J Antimicrob Agents, 48(4):373-380, 2016
32. Tsukada M, Sheng H, Kamachi T, Niwano Y: Microbicidal action of photoirradiated aqueous extracts from wine lees. J Food Sci Technol, 53(7):3020-3027, 2016
33. Ankyu S, Nakamura K, Harada A, Hong G, Kanno T, Niwano Y, Örtengren U, Egusa H: Fatigue analysis of computer-aided design/computer-aided manufacturing disilicate glass-ceramic. Eur J Oral Sci, 124(4):387-395, 2016
34. Tsukada M, Nakashima T, Kamachi T, Niwano Y: Prooxidative potential of photo-irradiated aqueous extracts of grape pomace, a recyclable resource from winemaking process. PLoS One, 11(6):e0158197, 2016
35. Tsukada M, Sheng H, Tada M, Mokudai T, Oizumi S, Kamachi T, Niwano Y: Bactericidal action of photo-irradiated aqueous extract from residue of crushed grape for wine preparation. Biocontrol Sci, 21(2):113-121, 2016
36. Nakamura K, Harada A, Ono M, Shibasaki H, Kanno T, Niwano Y, Milleding P, Örtengren U: Effect of low-temperature degradation on the mechanical and microstructural properties of tooth-colored 3Y-TZP ceramics. J Mech Behav Biomed Mater, 53:301-311, 2016
37. 庭野吉己：活性酸素による微生物制御．防菌防黴誌 44(3):119-124,2016
38. Tada M, Niwano Y, Kohno M: Generation mechanism of deferoxamine radical by tyrosine-tyrosinase reaction. Anal Sci, 31(9):911-916, 2015
39. Nakamura K, Katsuda Y, Ankyu S, Harada A, Tenkumo T, Kanno T, Niwano Y, Egusa H, Milleding P, Örtengren U: Cutting efficiency of diamond burs operated with electric high-speed dental handpiece on zirconia. Eur J Oral Sci, 123:375-380, 2015
40. Katsuda Y, Niwano Y, Nakashima T, Mokudai T, Nakamura K, Oizumi S, Kanno T, Kanetaka H, Egusa H: Cytoprotective effects of grape seed extract on human gingival fibroblasts in relation to its antioxidant potential. PLos ONE, 10(8): e0134704, 2015
41. Sheng H, Nakamura K, Kanno T, Sasaki K, Niwano Y : Bactericidal effect of photolysis of H2O2 in combination with sonolysis of water via hydroxyl radical generation. PLoS ONE, 10(7): e0132445, 2015
42. Nakamura K, Harada A, Kanno T, Inagaki R, Niwano Y, Milleding P, Örtengren U: The influence of low-temperature degradation and cyclic　loading on the fracture　resistance of monolithic zirconia molar crowns. J Mech Behav Biomed Mater, 47:49-56, 2015
43. Nakamura K, Ishiyama K, Sheng H, Ikai H, Kanno T, Niwano Y: Bactericidal activity and mechanism of photo-irradiated polyphenols against Gram-positive and -negative bacteria. J Agric Food Chem, 63(35):7707-7713, 2015
44. Harada A, Nakamura K, Kanno T, Inagaki R, Örtengren U, Niwano Y, Sasaki K, Egusa H: Fracture resistance of CAD/CAM-generated composite resin-based molar crowns. Eur J Oral Sci, 123(2):122-129, 2015
45. Nakamura K, Harada A, Inagaki R, Kanno T, Niwano Y, Milleding P, Örtengren U: Fracture resistance of monolithic zirconia molar crowns with reduced thickness. Acta Odontol Scand, 30:1-7, 2015
46. Mokudai T, Kanno T, Niwano Y: Postantifungal-like effect of sublethal treatment of Candida albicans with acid-electrolyzed water. Arch Oral Biol, 60(3):479-487, 2015
47. Mokudai T, Kanno T, Niwano Y: Involvement of reactive oxygen species in the cytotoxic effect of acid-electrolyzed water. J Toxicol Sci, 40(1):13-19, 2015
48. Toki T, Nakamura K, Kurauchi M, Kanno T, Katsuda Y, Ikai H, Hayashi E, Egusa H, Sasaki K, Niwano Y: Synergistic interaction between wavelength of light and concentration of H2O2 in bactericidal activity of photolysis of H2O2. J Biosci Bioeng, 119(3):358-362, 2015
49. Kurauchi M, Niwano Y, Shirato M, Kanno T, Nakamura K, Egusa H, Sasaki K: Cytoprotective effect of short-term pretreatment with proanthocyanidin on human gingival fibroblasts exposed to harsh environmental conditions. PLoS ONE, 9(11):e113403, 2014
50. Tada M, Kohno M, Niwano Y: Alleviation effect of arbutin on oxidative stress generated through tyrosinase reaction with L-tyrosine and L-DOPA. BMC Biochem, 15:23, 2014
51. Tsuruya M, Niwano Y, Nakamura K, Kanno T, Egusa H, Sasaki K: Acceleration of proliferative response of mouse fibroblasts by short-time pretreatment with polyphenols. Appl Biochem Biotechnol, 174(6):2223-2235, 2014
52. Niwano Y, Kanno T, Iwasawa A, Ayaki M, Tsubota K: Blue light injures corneal epithelial cells in the mitotic phase in vitro. Br J Ophthalmol, 98(7):990-992, 2014
53. Odashima Y, Nakamura K, Ikai H, Kanno T, Meirelles L, Sasaki K, Niwano Y: Postantibiotic effect of disinfection treatment by photolysis of hydrogen peroxide. J Chemother, 26(2):92-100, 2014
54. Sheng H, Nakamura K, Kanno T, Sasaki K, Niwano Y: Microbicidal activity of artificially generated hydroxyl radicals. Interface Oral Health Sci, 2014, pp203-215, 2014
55. Niwano Y, Iwasawa A, Ayaki M.: Ocular surface cytotoxicity and safety evaluation of tafluprost, a recently developed anti-glaucoma prostaglandin analogue. Ophthalmol Eye Dis, 6:5-12, 2014
56. Ikai H, Odashima Y, Kanno T, Nakamura K, Shirato M, Sasaki K, Niwano Y: In vitro evaluation of the risk of inducing bacterial resistance to disinfection treatment with photolysis of hydrogen peroxide. PLoS ONE, 8(11):e81316, 2013
57. Nakahara T, Harada A, Yamada Y, Odashima Y, Nakamura K, Inagaki R, Kanno T, Sasaki K, Niwano Y: Influence of a new denture cleaning technique utilizing photolysis of H2O2 on mechanical properties and color stability of acrylic denture base resin. Dent Mater J, 32(4):529-536, 2013
58. Iwasawa A, Ayaki M, Niwano Y: Cell viability score (CVS) as a good indicator of critical concentration of benzalkonium chloride for toxicity in cultured ocular surface cell lines. Regul Toxicol Pharmacol, 66(2):177-183, 2013
59. Ikai H, Nakamura K, Kanno T, Shirato M, Meirelles L, Sasaki K, Niwano Y: Synergistic effect of proanthocyanidin on the bactericidal action of the photolysis of H2O2. Biocontrol Sci, 18(2):137-141, 2013
60. Nakamura K, Shirato M, Ikai H, Kanno T, Sasaki K, Kohno M, Niwano Y: Photo-irradiation of proanthocyanidin as a new disinfection technique via reactive oxygen species formation, PLoS ONE, 8(3):e60053, 2013
61. Oyamada A, Ikai H, Nakamura K, Hayashi E, Kanno T, Sasaki K, Niwano Y: In vitro bactericidal activity of photo-irradiated oxydol products via hydroxyl radical generation. Biocontrol Sci, 18(2):83-88, 2013
62. Niwano Y, Iwasawa A, Ayaki M: Safety evaluation of ophthalmic moxifloxacin, an antibiotic of the fourth-generation fluoroquinolone family. J Symptoms Signs, 2(6):468-474, 2013
63. Ayaki M, Iwasawa A, Niwano Y: Comparative assessment of the cytotoxicity of six anti-inflammatory eyedrops in four cultured ocular surface cell lines, as determined by cell viability scores. Clin Ophthalmol, 6:1879-1884, 2012
64. Nakamura K, Yamada Y, Ikai H, Kanno T, Sasaki K, Niwano Y: Bactericidal action of photo-irradiated gallic acid via reactive oxygen species formation. J Agric Food Chem, 60(40):10048-10054, 2012
65. Beppu F, Hosokawa M, Niwano Y, Miyashita K: Effects of dietary fucoxanthin on cholesterol metabolism in diabetic/obese KK-Ay mice. Lipids Health Dis, 11(1):112, 2012
66. Mokudai T, Nakamura K, Kanno T, Niwano Y: Presence of hydrogen peroxide, a source of hydroxyl radicals, in acid electrolyzed water. PLoS ONE, 7(9):e46392, 2012
67. Nakamura K, Yamada Y, Takeda Y, Mokudai T, Ikai H, Inagaki R, Kanno T, Sasaki K, Kohno M, Niwano Y: Corrosive effect of hydroxyl radical generated by photolysis of H2O2 on dental metals. Dent Mater J, 31(6):941-946, 2012
68. Ishiyama K, Nakamura K, Ikai H, Kanno T, Kohno M, Sasaki K, Niwano Y: Bactericidal action of photogenerated singlet oxygen from photosensitizers used in plaque disclosing agents. PLoS ONE, 7(5):e37871, 2012
69. Hayashi E, Mokudai T, Yamada Y, Nakamura K, Kanno T, Sasaki K, Niwano Y: In vitro and in vivo anti-Staphylococcus aureus activities of a new disinfection system utilizing photolysis of hydrogen peroxide. J Biosci Bioeng, 114(2):193-197, 2012
70. Ayaki M, Iwasawa A, Niwano Y: Cell viability score as an integrated indicator for cytotoxicity of benzalkonium chloride-containing antiglaucoma eyedrops. Biocontrol Sci, 17(3):121-128, 2012
71. Ayaki M, Iwasawa A, Niwano Y: Comparative study of in vitro ocular surface cytotoxicity for fixed combination of 0.5% timolol/1% dorzolamide eyedrop and its components with 0.005% benzalkonium chloride. Biocontrol Sci, 17(3):115-120, 2012
72. Yamada Y, Mokudai T, Nakamura K, Hayashi E, Kawana Y, Kanno T, Sasaki K, Niwano Y: Topical treatment of oral cavity and wounded skin with a new disinfection system utilizing photolysis of hydrogen peroxide in rats. J Toxicol Sci, 37(2):329-335, 2012
73. Ayaki M, Iwasawa A, Niwano Y: In vitro assessment of six topical antibiotics cytotoxicity to　four cultured ocular surface cell lines. Biocontrol Sci, 17(2):93-99, 2012
74. Kanno T, Nakamura K, Ikai H, Hayashi E, Shirato M, Mokudai T, Iwasawa A, Niwano Y, Kohno M, Sasaki K: Novel denture cleaning system based on hydroxyl radical disinfection. Int J Prosthodont, 25(4):376-380, 2012
75. Yaekashiwa N, Sato E, Nakamura K, Iwasawa A, Kudo A, Kanno T, Kohno M, Niwano Y: Determination of reactive oxygen species generated by phorbol 12-myristate 13-acetate-stimulated oral polymorphonuclear cells from healthy human volunteers without any dental problems. Arch Oral Biol, 57:636-641, 2012
76. Nakamura K, Kanno T, Mokudai T, Iwasawa A, Niwano Y, Kohno M: Microbial resistance in relation to catalase activity to oxidative stress induced by photolysis of H2O2. Microbiol Immunol, 56(1):48-55, 2012
77. Shirato M , Ikai H, Nakamura K, Hayashi E, Kanno T, Sasaki K, Kohno M, Niwano Y: Synergistic effect of thermal energy on bactericidal action of photolysis of H2O2 in relation to acceleration of hydroxyl radical generation, Antimicrob Agents Chemother, 56(1):295-301, 2012
78. Iwasawa A, Niwano Y, Kohno M, Ayaki M: Virucidal activity of alcohol-based hand rub disinfectants. Biocontrol Sci, 17(1):45-59, 2012
79. Kanno T, Nakamura K, Ikai H, Kikuchi K, Sasaki K, Niwano Y: Literature review of the role of hydroxyl radicals in chemically-induced mutagenicity and carcinogenicity for the risk assessment of a disinfection system utilizing photolysis of hydrogen peroxide. J Clin Biochem Nutr, 51(1):9-14, 2012
80. Iwasawa A, Niwano Y, Kohno M, Ayaki M: Bactericidal effects and cytotoxicity of new aromatic dialdehyde disinfectants (ortho-phthalaldehyde). Biocontrol Sci, 16(4):165-170, 2011
81. Ayaki M, Iwasawa A, Niwano Y: Cytotoxicity assays of new artificial tears containing 2-methacryloyloxyethyl phosphorylcholine polymer for ocular surface cells. Jpn J Ophthalmol, 55(5):541-546, 2011
82. Sato E, Mokudai T, Niwano Y, Kohno M: Kinetic analysis of reactive oxygen species generated by the in vitro reconstituted NADPH oxidase and xanthine oxidase systems. J Biochem, 150(2):173-181, 2011
83. 岩沢篤郎、古田美香、菅野稔、目代貴之、河野雅弘、庭野吉己: 内視鏡洗浄用消毒装置CM-5の洗浄消毒効果．機能水研究, 6(1):15-25, 2011
84. Mokudai T, Kohno M, Niwano Y: Determination and speciation of vanadium(IV) and vanadium(V) in water sample by ion chromatography in combination with electron spin resonance analysis and/or electrolysis-induced reduction of vanadium(V). J Funct Water (機能水研究), 6(1):27-33, 2011
85. Kohno M, Mokudai T, Ozawa T, Niwano Y: Free radical formation from sonolysis of water in the presence of different gases. J Clin Biochem Nutr, 49(2):96-101, 2011
86. Nakamura K, Ishiyama K, Ikai H, Kanno T, Sasaki K, Niwano Y, Kohno M: Reevaluation of analytical methods for photogenerated singlet oxygen. J Clin Biochem Nutr, 49(2):87-95, 2011
87. Niwano Y, Saito K, Yoshizaki F, Kohno M, Ozawa T: Extensive screening for herbal extracts with potent antioxidant properties. J Clin Biochem Nutr, 48(1):78-84, 2011
88. Ikai H, Nakamura K, Shirato M, Kanno T, Iwasawa A, Sasaki K, Niwano Y, Kohno M: Photolysis of hydrogen peroxide, an effective disinfection system via hydroxyl radical formation. Antimicrob Agents Chemother, 54:5086-5091, 2010
89. Tada M, Kohno M, Kasai S, Niwano Y: Generation mechanism of radical species by tyrosine-tyrosinase reaction. J Clin Biochem Nutr, 47:162-166, 2010
90. Nakamura K, Kanno T, Ikai H, Sato E, Mokudai T, Niwano Y, Ozawa T, Kohno M: Reevaluation of quantitative ESR spin trapping analysis of hydroxyl radical by applying sonolysis of water as a model system. Bull Chem Soc Jpn, 83:1037-1046, 2010
91. Nakamura K, Kanno T, Mokudai T, Iwasawa A, Niwano Y, Kohno M: A novel analytical method to evaluate directly catalase activity of microorganisms and mammalian cells by ESR oximetry. Free Radic Res, 44:1036-1043, 2010
92. Kim D, Cha SH, Sato E, Niwano Y, Kohno M, Jiang Z, Yamasaki Y, Matsuyama Y, Yamaguchi K, Oda T: Evaluation of the potential biological toxicities of aqueous extracts from red tide phytoplankton cultures in in vitro and in vivo systems. J Toxicol Sci, 35:591-599, 2010
93. Nakashima T, Seki T, Matsumoto A, Miura H, Sato E, Niwano Y, Kohno M, Ōmura S, Takahashi Y: Generation of Reactive Oxygen Species from conventional laboratory media. J Biosci Bioeng, 110:304-307, 2010
94. Tada M, Kohno M, Niwano Y: Scavenging or quenching effect if melanin on superoxide anion and singlet oxygen. J Clin Biochem Nutr, 46:224-228, 2010
95. Yamashita Y, Hoshino T, Matsuda M, Kobayashi C, Mineda K, Maji D, Niwnao Y, Mizushima T: HSP70 inducers from Chinese herbs and their effect on melanin production. Exp Dermatol, 19:e340-e342, 2010
96. Beppu F, Niwano Y, Sato E, Kohno M, Tsukui T, Hosokawa M, Miyashita K: In Vitro and in vivo evaluation of mutagenicity of fucoxanthin and Its metabolite fucoxanthinol. J Toxicol Sci, 34:693-698, 2009
97. Beppu F, Niwano Y, Tsukui T, Hosokawa M, Miyashita K: Single and repeated oral dose toxicity study of fucoxanthin, a marine carotenoid, in mice. J Toxicol Sci, 34:501-510, 2009
98. Iwasawa A, Saito K, Mokudai T, Kohno M, Ozawa T, Niwano Y: Fungicidal action of hydroxyl radicals generated by ultrasound in water. J Clin Biochem Nutri, 45:214-218, 2009
99. Tada M, Ichiishi E, Saito R, Emoto N, Niwano Y, Kohno M: Myristic acid, a side chain of phorbol myristate acetate (PMA), can activate human polymorphonuclear leukocytes to produce oxygen radicals more potently than PMA. J Clin Biochem Nutr, 45:309-314, 2009
100. Iwasawa A, Saito K, Mokudai T, Kohno M, Ozawa T, Niwano Y: Fungicidal action of hydroxyl radicals generated by ultrasound in water. J Clin Biochem Nutr, 45:214-218, 2009
101. Iwasawa A, Niwano Y, Mokudai T, Kohno M: Antiviral activity of proanthocyanidin against feline calicivirus used as a surrogate for noroviruses, and coxsackievirus used as a representative enteric virus. Biocontrol Sci 14:107-111, 2009
102. Niwano Y, Beppu F, Shimada T, Kyan R, Yasura K, Tamaki M, Nishino M, Midorikawa Y, Hamada H: Extensive screening for plant foodstuffs in Okinawa, Japan with anti-obese activity on adipocytes in vitro. Plant Foods Hum Nutr, 64:6-10, 2009
103. 樫村淳、足立堯、木下真紀、坂田隆、佐々木一、高橋英樹、中村義幸、庭野吉己、根崎裕子、福原公昭、夜久俊治、米久保明得、木村修一：果糖と脂質代謝　－特に肥満との関係を中心として－．日本食品新素材研究会誌 12:49-55, 2009
104. Niwano Y, Adachi T, Kashimura J, Sakata T, Sasaki H, Sekine K, Yamamoto S, Yonekubo A, Kimura S: Is Glycemic Index of Food a Feasible Predictor of Appetite, Hunger, and Satiety? J Nutr Sci Vitaminol, 55:201-207, 2009
105. Kohno M, Sato E, Yaekashiwa N, Mokudai T, Niwano Y: Proposed Mechanisms for HOOOH Formation in Two Typical Enzyme Reactions Responsible for Superoxide Anion Production in Biological Systems. Chem Lett, 38:302-307, 2009
106. Saito K, Kohno M, Yoshizaki F, Niwano Y: Antioxidant properties of herbal extracts selected from screening for potent scavenging activity against superoxide anions. J Sci Food Agric, 88:2707-2712, 2008
107. Kohno M, Takeda M, Niwano Y, Saito R, Emoto N, Tada M, Kanazawa T, Ohuchi N, Yamada R: Early diagnosis of cancer by detecting the chemiluminescence of hematoporphyrins in peripheral blood lymphocytes. Tohoku J Exp Med, 216:47-52, 2008
108. Sato E, Mokudai T, Niwano Y, Kamibayashi M, Kohno M: Existence of a New Reactive Intermediate Oxygen Species in Hypoxanthine and Xanthine Oxidase Reaction. Chem Pharm Bull, 56:1194-1197, 2008
109. Nakashima T, Niwano Y, Takeshita S:Effects of antifungal agents on the red tide phytoplankton –possibility of a novel preventive tool- Aquaculture Res 39:1346-1350, 2008
110. Saito K, Kohno M, Yoshizaki F, Niwano Y: Extensive screening for edible herbal extracts with potent scavenging activity against superoxide anions. Plant Foods Hum Nutr, 63:65-70, 2008
111. Nakashima T, Iwashita T, Fujita T, Sato E, Niwano Y, Kohno M, Kuwahara S, Harada N, Takeshita S, Oda T: A prodigiosin analogue inactivates NADPH oxidase in macrophage cells by inhibiting assembly of p47phox and Rac. J Biochem, 143:107-115, 2008
112. Sato E, Kohno M, Nakashima T, Niwano Y: Ciclopirox olamine directly scavenges hydroxyl radical. Int J Dermatol, 47:15-18, 2008
113. Niwano Y, Mitsui G, Kohno M: Chemokines and their receptors as a target for the treatment of contact hypersensitivity. J Anti-Inflamm Anti-Allergy Agents Med Chem, 7:45-51, 2008
114. Sachindra NM, Sato E, Maeda H, Hosokawa M, Niwano Y, Kohno M, Miyashita K: Radical scavenging and singlet oxygen quenching activity of marine carotenoid fucoxanthin abd its metabolites. J Agric Food Chem, 55:8516-8522, 2007
115. Kim D, Nakashima T, Matsuyama Y, Niwano Y, Yamaguchi K, Oda T: Presence of the distinct systems responsible for superoxide anion and hydrogen peroxide generation in red tide phytoplankton Chatonella marina and Chatonella ovata. J Plankton Res29:241-247, 2007
116. Sato E, Niwano Y, Mokudai T, Kohno M, Matsuyama Y, Kim D, Oda T: A Discrepancy in Superoxide Scavenging Activity between the ESR-Spin Trapping Method and the Luminal Chemiluminescence Method. Biosci Biotechnol Biochem, 71:1505-1513, 2007
117. Niwano Y, Sato E, Kohno M, Matsuyama Y, Kim D, Oda T: Antioxidant Properties of the Aqueous Extracts from Red Tide Plankton Cultures. Biosci Biotechnol Biochem, 71:1145-1153, 2007
118. Sato E, Niwano Y, Matsuyama Y, Kim D, Nakashima T, Oda T, Kohno M: Some Dinophycean Red Tide Plankton Species Generate a Superoxide Scavenging Substance. Biosci Biotechnol Biochem, 71:704-710, 2007
119. Sato E, Kato M, Kohno M, Niwano Y: Clindamycin phosphate scavenges hydroxyl radical Int J Dermatol, 46:1185-1187, 2007
120. Nakashima T, Sato E, Niwano Y, Kohno M, Muraoka W, Oda T: Inhibitory or scavenging action of ketoconazole and ciclopirox olamine against reactive oxygen species released by primed inflammatory cells. Br J Dermatol, 156:720-727, 2007
121. Sato E, Kohno M, Niwano Y: Increased level of tetrahydro-β-carboline derivatives in short-term fermented garlic. Plant Foods Hum Nutr, 61:175-178, 2006
122. Sato E, Kohno M, Hamano H, Niwano Y: Increased anti-oxidative potency of garlic by spontaneous short-term fermentation. Plant Foods Hum Nutr, 61:157-160, 2006
123. Gu Y, Takagi Y, Nakamura T, Hasegawa T, Suzuki I, Oshima M, Tawaraya H, Niwano Y: Enhancement of radioprotection and anti-tumor immunity by yeast-derived β-glucan in mice. J Med Food, 8:154-158, 2005
124. Nishizawa M, Kohno M, Nishimura M, Kitagawa A, Niwano Y: Presence of peroxyradicals in cigarette smoke and the scavenging effect of shikonin, a naphthoquinone pigment. Chem Pharm Bull, 53:796-799, 2005
125. Nishizawa M, Kohno M, Nishimura M, Kitagawa A, Niwano Y: Non-reductive scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) by peroxyradical –A useful method for quantitative analysis of peroxyeradical-. Chem Pharm Bull, 53:714-716, 2005
126. Mitsui G, Hirano T, Niwano Y, Mitsui K, Ohara O, Yanagihara S, Kato M: Effect of a topical steroid on gene expressions for chemokines in mice with contact hypersensitivity. Int Immunopharmacol, 4:57-69, 2004
127. Nimura K, Niwano Y, Ishizuka S, Fukumoto R: Actin gene-targeted RT-PCR could be a useful method for evaluating fungicidal activity against dermatophyte in vitro. J Int Med Res, 31:407-412, 2003
128. Mitsui G, Mitsui K, Hirano T, Ohara O, Kato M, Niwano Y: Kinetic profiles of sequential expressions for chemokine genes in mice with contact hypersensitivity. Immunol Lett, 86:191-197, 2003
129. Niwano Y, Ohmi T, Seo A, Kodama H, Koga H, Sakai A: Lanoconazole and its related optically active compound NND-502: Novel antifungal imidazoles with a ketene dithioacetal structure. Curr Med Chem–Anti-Infect Agents-, 2:147-160, 2003
130. Nimura K, Niwano Y, Ishizuka S, Fukumoto R: Comparison of in vitro antifungal activities of topical antimycotics launched in 1990’s in Japan. Int J Antimicrob Agents, 18(2):173-178, 2001

2000年以前は省略